Comparative Imaging Assessment of Valvular Heart Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorThe Cleveland Clinic
About this trial
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.
Eligibility criteria
Qualifiers
Age 18-90 years of age
Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
Suspected CRT "non-responder" with an implanted MRI compatible CRT device and reduced ejection fraction
Disqualifiers
Acute traumatic cardiac injury
Aortic dissection or aortic root rupture
Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
Presence of A-V fistula or intracardiac shunts
Trial design
Treatments tested in this trial
- MRI with strain measurement
- Echocardiography
Treatment groups
200 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov