This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT) autograft or a Hamstring Tendon (HST) autograft. The primary objective is to compare early functional outcomes between the two groups at 6 weeks and 3 months post-surgery, using the Lysholm Knee Score. The study aims to demonstrate the non-inferiority of the PLT graft. All surgeries will be performed arthroscopically at Khyber Teaching Hospital, Peshawar, followed by a standardized rehabilitation protocol.
Patients aged 18 years or older.
Isolated, primary Anterior Cruciate Ligament (ACL) injury confirmed by clinical assessment and Magnetic Resonance Imaging (MRI).
Provides written informed consent for the surgical procedure and study participation, including follow-up assessments.
Multiligament knee injuries (e.g., concomitant PCL, MCL, or LCL injuries).
Previous surgery or history of fracture in the involved lower limb.
Radiographic evidence of osteoarthritis in the affected knee.
Presence of any neuromuscular disease.
Khyber Medical University Peshawar
Lead sponsor
Khyber Medical College, Peshawar
Collaborator