Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-85
SponsorThammasat University Hospital
About this trial
The goal of this RCT is to compare efficacy between mirogabalin and pregabalin in pain reducing after unilateral primary total knee arthroplasty.
The main question\[s\] it aims to answer are:
• Does mirogabalin have better pain reduction than pregabalin after unilateral primary total knee arthroplasty.
Participants will randomized to mirogabalin or pregabalin group and will take the drug for 6 weeks after TKA. Researchers will compare to pregabalin group to see pain and functional outcomes after TKA.
Eligibility criteria
Qualifiers
Age 50-85 years old
Unilateral primary osteoarthritis undergoing primary TKA
ASA I-III
Disqualifiers
GFR <60
Allergy to drug in this study
Cannot underwent spinal anesthesia and adductor canal block
Taking gabapentinoid within 3 months before surgery
Trial design
Treatments tested in this trial
- Mirogabalin
- Pregabalin
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov