The goal of this clinical trial is to determine the optimal protein administration strategy for enhancing both nutritional and clinical outcomes, as well as reducing complications and mortality in ICU patients at risk for refeeding syndrome (RS). This study will include critically ill patients at risk for RS who are receiving supportive nutrition. The primary hypothesis is that higher protein intake will lead to a decreased incidence of refeeding syndrome. It is also expected that patients receiving more protein will have better clinical outcomes, lower mortality, and shorter ICU and hospital stays.
Willingness to cooperate and complete the informed consent form by the patient or legal guardian;
age ≤ 18 years and < 65 years;
Non-pregnant and non-lactating;
Serum creatinine ≥ 1.1 mg/dl for women and ≥ 1.2 mg/dl for men;
Unwillingness to continue cooperation during study;
Discharge or death of the patient earlier than 5 days from the start of the intervention;
Occurrence of side effects during the study
Shahid Beheshti University
Lead sponsor
Shahid Beheshti University of Medical Sciences
Sponsor institution