Comparing PCCT With ICA and IVUS in Detecting Cardiac Allograft Vasculopathy

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSahlgrenska University Hospital

About this trial

In traditional coronary artery disease, patients often experience symptoms such as angina. However, heart transplant patients lack nerve connections in the transplanted heart and therefore usually do not notice any symptoms. For this reason, routine examinations are performed using traditional coronary angiography at one, three, and six years after transplantation, sometimes with the addition of coronary ultrasound.

A new technique, photon-counting computed tomography, has now been developed and may potentially replace both traditional coronary angiography and intravascular ultrasound. In this study, we aim to investigate how well this method works in diagnosing coronary artery changes compared to the established methods.

Eligibility criteria

Qualifiers

Adult heart transplant recipients.

Clinically stable and scheduled for routine ICA.

Ability to provide informed consent

Disqualifiers

Contrast allergy

Renal insufficiency with eGFR < 30 ml/min/m2

Other contraindications for PCCT, ICA, or IVUS

Acute cardiac events within 30 days prior to enrollment.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

Sahlgrenska University Hospital

Lead sponsor

Göteborg University

Collaborator