About this trial
Many people in the US suffer from chronic pain. Often times, individuals who have chronic pain also feel depressed, anxious, or hopeless, which can worsen pain. Psychologists, therefore, have developed several treatments to help people with chronic pain. These psychological treatments differ. The most common treatment is Cognitive Behavioral Therapy (CBT) for chronic pain, which helps patients better manage pain through changing thoughts and behaviors. Two newer, less common psychological therapies are Pain Reprocessing Therapy (PRT) and Emotion Awareness and Expression Therapy (EAET). These therapies emphasize that chronic pain is mainly due to plastic processes of over-sensitization in the brain and nervous system, and that psychotherapies can significantly reduce or eliminate pain. Although similar, PRT and EAET stress different aspects of treatment. PRT emphasizes that one's fear of pain and bodily injury maintains the brain's sense of threat, thereby also maintaining the pain response; EAET emphasizes that one's conditioned psychological state of stress and tension maintains a sense of threat, thereby maintaining the pain response. These three treatments have yet to be compared; it is unclear which psychological processes are most important to treating chronic pain.
There is growing interest in single-session psychotherapy interventions. Studies have shown that just a single session of CBT or EAET can help individuals reduce their pain. PRT has yet to be condensed to a single-session intervention.
This study will compare a single session of CBT, PRT, and EAET with a no-treatment control group to test whether 1) one treatment outperforms the others, and 2) different mechanisms/ approaches matter to chronic pain treatment.
Eligibility criteria
Qualifiers
Pain for at least 3 months and experienced 4 or more days/week for the past 6 months
Pain intensity last week is >= 3 (0 to 10 rating scale)
Pain interference last week is >= 3 (0 to 10 rating scale)
At least age 18
Disqualifiers
Complex regional pain syndrome
Epilepsy/seizure disorder
Autoimmune disease
Liver disease
Trial design
Treatments tested in this trial
- Cognitive Behavioral Therapy
- Pain Reprocessing Therapy
- Emotion Awareness and Expression Therapy
Treatment groups
Sponsors and collaborators
Mark A. Lumley
Lead sponsor
Wayne State University
Sponsor institution