Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-75
SponsorECOG-ACRIN Cancer Research Group

About this trial

The purpose of this study is to compare two approaches for monitoring pancreatic cysts as well as to identify associated biomarkers. The study doctors want to compare more frequent monitoring versus less frequent monitoring as well as identify biomarkers which may improve risk detection of transformation to pancreatic cancer. The study doctors want to learn which monitoring method and which biomarkers lead to better outcomes for patients.

Eligibility criteria

Qualifiers

Patient must be ≥ 50 years and ≤ 75 years of age

Patient must not have acute pancreatitis or a history of chronic pancreatitis

Patient must have received a CT, MRI, or EUS within 6 months prior to enrollment that revealed one or more ≥ 1 cm pancreatic cyst(s).

Patients of childbearing potential must not be known to be pregnant

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Biopsy Procedure
  • Biospecimen Collection
  • Computed Tomography
  • Endoscopic Ultrasound
  • Endoscopic Ultrasound-Guided Fine-Needle Aspiration
  • Magnetic Resonance Imaging
  • Quality-of-Life Assessment
  • Questionnaire Administration
  • Surgical Procedure

Treatment groups

770 Participants
are divided into 3 treatment groups

Sponsors and collaborators

ECOG-ACRIN Cancer Research Group

Lead sponsor

National Cancer Institute (NCI)

Collaborator