Comparing the Efficacy of Surgery Staging and Image Staging of Locally Advanced Cervical Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorChongqing University Cancer Hospital

About this trial

The study is a domestic multicenter, prospective, non-randomized controlled concurrent trial. It will be assessed whether surgery staging on locally advanced cervical cancer is superior to image staging for improving progression-free survival and overall survival.

Eligibility criteria

Qualifiers

The patients with good compliance, voluntarily signed the informed consent form and participated in the study.

Histopathology: squamous cell carcinoma, adenocarcinoma, adenosquamous cell carcinoma

Stage (FIGO2018): IB3, IIA2, IIB-IVA;

ECOG score: 0 ~ 1;

Disqualifiers

Activity or uncontrol severe infection;

Liver cirrhosis or other decompensated liver disease;

A history of immune deficiency, including HIV positive or a congenital immunodeficiency disease;

Chronic renal insufficiency or renal failure;

Trial design

Treatments tested in this trial

  • Concurrent chemoradiation
  • Open/minimally invasive para-aortic lymph node dissection followed by concurrent chemoradiation

Treatment groups

1,956 Participants
are divided into 2 treatment groups