Comparing Three Rescue Bowel Preparation Regimens for Colonoscopy After Failed Cleansing

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorOspedale San Pio

About this trial

The goal of this clinical trial is to learn which rescue bowel preparation works best for adults who need a repeat colonoscopy after a previous bowel preparation did not clean the bowel well enough. The study will also look at how satisfied participants are with each preparation. The main questions it aims to answer are:

* Which bowel preparation helps more participants achieve adequate bowel cleansing before repeat colonoscopy? * Which bowel preparation leads to better cleansing in different parts of the colon? * Which bowel preparation is better tolerated by participants?

Researchers will compare 3 rescue bowel preparation regimens to see which one works best for repeat colonoscopy after a previous cleansing failure.

Participants will:

* be randomly assigned to 1 of 3 bowel preparation regimens * take one of the following regimens before repeat colonoscopy: * 4 liters of polyethylene glycol (PEG) plus 12 milligrams of bisacodyl * 1 liter of PEG plus ascorbic acid plus 10 milligrams of bisacodyl * 2 liters of PEG plus extra PEG taken over the 3 days before colonoscopy * undergo repeat colonoscopy * rate their satisfaction with the bowel preparation

Eligibility criteria

Qualifiers

Adults aged 18 years or older

Prior inadequate bowel preparation (adequately performed) requiring repeat colonoscopy

Scheduled to undergo repeat outpatient colonoscopy

Ability to provide informed consent

Disqualifiers

Age younger than 18 years

Inability to provide informed consent

Contraindication to any study bowel preparation regimen or colonoscopy

Known or suspected bowel obstruction or severe gastrointestinal motility disorder

Trial design

Treatments tested in this trial

  • Drug
  • Drug
  • Drug

Treatment groups

220 Participants
are divided into 3 treatment groups

Sponsors and collaborators