Comparing Three Surgical Techniques for the Treatment of Transsphincteric Perianal Fistula: (1) Traditional Fistulotomy (Lay Open), (2) Ligation of the Intersphincteric Tract (LIFT) With Adjunctive Endo Fistula Laser Ablation, and (3) Open LIFT Procedure Followed by LASER

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAlexandria University

About this trial

\>This randomized clinical trial compares three different surgical techniques for the treatment of transsphincteric perianal fistula: (1) traditional fistulotomy (lay open), (2) ligation of the intersphincteric tract (LIFT) with adjunctive endofistula laser ablation, and (3) open LIFT procedure followed by direct laser ablation of the tract under vision. The aim is to determine which approach offers the highest healing rate, lowest recurrence, and best postoperative outcomes with minimal impact on continence.

Eligibility criteria

Qualifiers

Adults aged 18-65

Confirmed diagnosis of transsphincteric cryptoglandular perianal fistula

Primary (first-time) surgery

Able to provide informed consent

Disqualifiers

Crohn's disease or other inflammatory bowel disease

Suprasphincteric, extrasphincteric, or horseshoe fistulas

Previous fistula surgery

Active perianal abscess

Trial design

Treatments tested in this trial

  • fistula lay open
  • LIFT plus LASER
  • open LIFT plus LASER

Treatment groups

90 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators