Comparing Two Therapies to Improve Arm Function After Stroke
ConditionStroke
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-65
SponsorUniversity of Lahore
About this trial
This clinical trial aims to compare the effects of coupling rehabilitation and constraint-induced movement therapy (CIMT) on improving arm function, hand skills, and daily activity performance in people who have upper limb weakness after a stroke. Participants will be randomly assigned to one of two groups and receive 12 weeks of therapy, including either CIMT or coupling rehabilitation along with conventional physical therapy. The study will evaluate which method is more effective in restoring movement and independence by using standardized assessments before, during, and after the intervention. The findings may help guide future rehabilitation approaches for stroke survivors
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients suffering from Sub acute stroke
Motor function score at Fugl-Meyer Assessment between 40-60
Fine motor assessment at Box and Block Test<20
Disqualifiers
Individuals suffering from unstable angina, symptomatic heart failure, or uncontrolled hypertension
Physician determined unstable cardiovascular conditions
The patient has been diagnosed as having organ failure, including the heart, kidneys, and lungs
Patients with any traumatic musculoskeletal injury to upper limbs
Trial design
Design model
Parallel
Treatments tested in this trial
Constraint-Induced Movement Therapy (CIMT)
Other interventionParticipants in this group will receive modified CIMT in combination with conventional physical therapy. The unaffected arm will be restrained to encourage use of the affected upper limb. Task-specific exercises will include fine motor tasks, strengthening, reaching, and functional movement training. Each session will last approximately 45-60 minutes and will be conducted three times per week for 12 weeks.
Coupling Rehabilitation
Other interventionParticipants in this group will receive Coupling Rehabilitation in addition to conventional physical therapy. This method involves bilateral arm training and functional tasks designed to improve coordination between both upper limbs, using the unaffected limb to guide movement in the affected one. Exercises will include trunk-supported reaching, object retrieval, and posture-supported task practice. Sessions will occur three times per week for 12 weeks, each lasting approximately 45-60 minutes.
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: Constraint-Induced Movement Therapy (CIMT) GroupExperimental treatment 1 intervention
Group B: Coupling Rehabilitation GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Improvement in Upper Limb Motor Function Using the Fugl-Meyer Assessment (FMA)
This outcome assesses changes in motor control and function of the affected upper limb using the Fugl-Meyer Assessment, a validated stroke-specific performance test. Higher scores reflect better motor recovery.
Time frame
Baseline, 6 weeks, and 12 weeks after start of intervention2
Change in Hand Dexterity Using the Box and Block Test (BBT)
This outcome evaluates fine motor skills and hand coordination by measuring the number of blocks a participant can move from one compartment to another in one minute using the affected hand. Higher scores indicate better hand dexterity.
Time frame
Baseline, 6 weeks, and 12 weeks after start of intervention3
Change in Performance of Daily Activities Using the Motor Activity Log (MAL)
This outcome assesses real-world use of the affected upper limb in daily activities using the MAL questionnaire. It includes two subscales: Amount of Use (AOU) and Quality of Movement (QOM). Higher scores indicate better function and limb use.
Time frame
Baseline, 6 weeks, and 12 weeks after start of interventionSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: