About this trial
The goal of this clinical trial is to learn if norepinephrine is more effective than phenylephrine for prevention of spinal anesthesia induced hypotension. The main questions it aims to answer are:
Does norepinephrine lower the incidence of spinal anesthesia induced hypotension in emergency obstetrical patients? We will compare effectiveness of norepinephrine and phenylephrine for the prevention of spinal anesthesia induced hypotension.
Participants will:
Be administered prophylactic boluses of both drugs right after spinal anesthesia induction and maternal hemodynamic parameters and neonatal APGAR scores will be recorded
Eligibility criteria
Qualifiers
American society of anesthesiologists II and III patients
Age 18-40years
Gestational age 32 weeks and above
Disqualifiers
Patients with hypertensive disorders of pregnancy having baseline systolic blood pressure greater than 160 mmHg and diastolic blood pressure greater than 99 mmHg.
Baseline mean arterial pressure less than 70 mmHg.
Antepartum hemorrhage/intraoperative blood loss greater than 1000ml
history indicative of cardiovascular or neurological disease.
Trial design
Treatments tested in this trial
- Norepinephrine Bolus
- Phenylephrine bolus