Comparison Immune Response in Paravertebral and Erector Spinal Plane Block in Breast Cancer Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-70
SponsorClinical Hospital Center Rijeka

About this trial

The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer.

The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block.

Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block.

Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.

Eligibility criteria

Qualifiers

ASA I and ASA II status, normal BMI

Disqualifiers

ASA III and ASA IV status, coagulopathy, chronic opioid use, diabetes, local infection of the skin

Trial design

Treatments tested in this trial

  • Regional Anesthetic Injection
  • Blood draw for the laboratory assessment
  • Blood draw for the laboratory assessment

Treatment groups

56 Participants
are divided into 3 treatment groups

Locations

This trial has no locations