This is a randomized, single-center clinical trial that will compare the efficacy of two substances used in the submucosal cushion formation stage of endoscopic submucosal resections of early esophageal malignant neoplasms. Such substances are hyaluronic acid in the form of TS-905 Blue Eyeₒ and hydroxyethylamide (Voluven®).
Patients over 18 years of age
Superficial esophageal adenocarcinoma or squamous cell carcinoma with indication of ESD after discussion in a multidisciplinary oncological board
Signed informed consent form
Residual or recurrent esophageal lesions
Ulcerated esophageal lesions
Patients with severe cardiovascular, kidney or liver disease
History of hypersensitivity to hyaluronic acid