This randomized controlled trial aims to compare the anesthetic efficacy of 2% lignocaine administered through an inferior alveolar nerve block (IANB) in one group of participants with 4% articaine delivered via primary buccal infiltration in other group in patients with symptomatic irreversible pulpitis in mandibular first molars.
Systemically healthy patients classified as ASA I, aged 18-55 years.
Permanent mandibular first molar tooth requiring endodontic therapy.
Diagnosed with symptomatic irreversible pulpitis without swelling or sinus.
Normal periapical radiographic appearance (no evidence of periapical pathology).
• Pregnant or lactating mothers.
Teeth with reversible pulpitis, previously treated, or with calcified canals.
Teeth with severe periodontal disease or periapical radiolucency.
Patients who have taken analgesics or anti-inflammatory drugs within 6 hours before the treatment visit.
Armed Forces Institute of Dentistry, Pakistan
Lead sponsor
Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi
Sponsor institution