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Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment

ConditionsGingivitisDental Plaque
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age13-40
SponsorKhyber Medical University Peshawar

About this trial

This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment. Gingival Index and Plaque Index will be assessed at baseline, 2 weeks, and 4 weeks.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Aged 13-40 years

Permanent dentition (including first molars)

Willing to undergo orthodontic treatment and follow instructions

Disqualifiers

Systemic illness (e.g., diabetes, heart disease, hepatitis)

Pregnant/lactating females

Tobacco use

History of allergies to mouthwash/toothpaste

Trial design

Design model

Parallel

Treatments tested in this trial

  • Listerine Mouthwash Product

    Drug

    Participants in this group will receive Listerine mouthwash containing essential oils (menthol, thymol, eucalyptol, and methyl salicylate). They will be instructed to rinse once daily with 10 ml of the solution for 30 seconds after brushing, over a period of 4 weeks. The mouthwash will be dispensed in unlabelled bottles to maintain blinding. Standard oral hygiene instructions will be given.

  • Chlorhexidine mouthwash

    Drug

    Participants in this group will receive Chlorhexidine mouthwash at a concentration of 0.12%. They will be instructed to rinse once daily with 10 ml of the solution for 30 seconds after brushing, over a period of 4 weeks. The mouthwash will be dispensed in unlabelled bottles to maintain blinding. Standard oral hygiene instructions will be given.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Listerine GroupExperimental treatment 1 intervention
Group B: Chlorhexidine GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Gingival Index (GI)

Measured using standard GI scale (Grades 0-3)

Time frame
baseline, 2 weeks, and 4 weeks , 8 week
2

Plaque Index (PI)

Measured using Orthodontic Plaque Index (Grades 0-4)

Time frame
baseline, 2 weeks, and 4 weeks , 8 week

Secondary outcomes

1

Side effects

The side effects of the trial will be noted in the adverse event log frame.

Time frame
Baseline till 8 weeks

Other outcomes

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

Saidu College of DentistryRecruiting Swāt, KPKPakistanPakistan

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Khyber Medical University Peshawar

Lead sponsor

Saidu College of Dentistry

Collaborator

Source ClinicalTrials.gov
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