Comparison of Debridement, Antibiotic, Implant Retention and Implant Exchange in Early-stage Fracture-related Infections

ConditionsOrthopedic Surgery Fracture Related Infection Debridement Implant Retention Implant Removal/Replacement

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorAntalya Health Sciences University

About this trial

This study aims to compare the clinical outcomes of debridement, antibiotics, and implant retention (DAIR) and implant removal/replacement methods used in the treatment of fracture-related infections, and to determine the infection-free fracture healing rates and the factors affecting treatment success.

Eligibility criteria

Qualifiers

internal fixation after fracture

presence of fistula and/or sinus tract or purulent drainage with dehiscence at the incision site

at least 2 positive deep tissue cultures or at least 3 positive soft tissue cultures

early onset of symptoms (6 weeks)

Disqualifiers

Under 18 years old patients

prosthetic joint infection

only conservative treatment applied

pathological fracture due to primary bone tumor

Trial design

Treatments tested in this trial

DAIR
Implant removal/replacement

Treatment groups

75 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Antalya Health Sciences University

Lead sponsor

Source ClinicalTrials.gov