Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorQilu Hospital of Shandong University
About this trial
This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertiary hospitals, who underwent either double-tract reconstruction (DTR) or tubular gastric anastomosis (TGA). Participants were divided into two groups based on the surgical procedure. We conducted a comparative analysis of postoperative outcomes by evaluating electronic medical records, postoperative gastroscopy, 24-hour esophageal pH monitoring, and relevant rating scales.
Eligibility criteria
Qualifiers
Pathologically confirmed gastric adenocarcinoma by biopsy
Carcinoma of the upper gastric body or Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG), with a clinical stage of cT1-3N0-1M0
Age 18-75 years, with a performance status (PS) score of 0-2
Candidates for planned surgical resection, eligible for either double-tract reconstruction or tubular gastric anastomosis based on preoperative assessment
Disqualifiers
Presence of other malignant tumors or severe chronic diseases (e.g., severe diabetes mellitus, chronic kidney disease, decompensated cirrhosis, etc.)
Preoperative endoscopic diagnosis of Barrett's esophagus
Severe preoperative malnutrition (albumin <30 g/L, prealbumin <150 mg/L)
History of prior upper abdominal surgery, gastrointestinal malformation, or psychiatric disorders
Trial design
Treatments tested in this trial
- Double-tract reconstruction
Treatment groups
52 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov