Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRuijin Hospital
About this trial
This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.
Eligibility criteria
Qualifiers
Age ≥18 years
Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions)
ASA physical status class I-III
Disqualifiers
History of chronic pain or long-term use of analgesics prior to surgery
Severe cardiopulmonary dysfunction (e.g., FEV1 <50%)
Coagulation disorders or patients undergoing reoperation
Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion
Trial design
Treatments tested in this trial
- Chest mediastinal tube
- Abdominal mediastinal tube
- Chest tube + chest mediastinal tube
Treatment groups
75 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov