This Research is a clinical study with a single-blind randomized controlled trial of evaluators. Clinical trial Randomized Controlled Trial (RCT) design that compares the use of a triple combination cream of flucinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05% with a triple cream combination of mometasone furoate 0.1%, hydroquinone 4%, tretinoin 0.05% in melasma therapy in RSCM-FKUI.
This study aims to Assess the effectiveness and safety of Triple Combination Cream of Fucinolone Acetonide 0.01%, Hydroquinone 4%, Tretinoin 0.05% with Mometasone Furoate 0.1%, Hydroquinone 4%, Tretinoin 0.05% in melasma patients
Women
Diagnosed with melasma based on clinical and Wood's lamp examination
30-59 years old
Skin type IV or V
Plan to be pregnant and breastfeeding women during the study period ( 12 weeks)
using or have used hormonal contraception in the last 6 months, or plan to use hormonal contraception during the study period (12 weeks)
Using topical melasma treatments such as corticosteroids, tretinoin, hydroquinone, and other skin whitening or lightening treatments in at least the last 2 weeks.
Have used topical therapy for melasma i.e. triple combination cream for at least 3 months and showed no significant improvement.
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Indonesia