Comparison of FNB to EUS-CNB for Pancreatic Lesions
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-89
SponsorUniversity of California, Davis
About this trial
The primary aim of this study is to compare the tissue specimen quality and diagnostic accuracy of biopsies obtained with one puncture of a regular 22 FNB G needle and the motorized EUS CNB device of pancreatic lesions. The secondary aims are to compare the rate of blood contamination in the specimens obtained from biopsies of pancreatic lesions and the overall procedure duration. The hypothesis of this study is that the proportion of cases in which a single puncture of the lesion in question delivers adequate diagnostic tissue is higher with the motorized EUS CNB than with the 22 G FNB.
Eligibility criteria
Qualifiers
Patients who require EUS and tissue sampling of pancreatic solid lesions (size> 2.5 cm)
Patients who can give consent
Disqualifiers
patients without pancreatic lesions
Pregnant females
Hematologic and Coagulation disorders (platelets < 50,000/mm3, INR > 2, ANC <1000)
Patients with acute pancreatitis in the immediate 2 weeks before the procedure (if the lesion to be biopsied is in the pancreas)
Trial design
Treatments tested in this trial
- endoscopic ultrasound guided biopsy with core needle biopsy device
- EUS-FNB
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov