Benign prostatic hyperplasia (BPH) is a common condition in aging men and may require surgical treatment when medical therapy is ineffective. Anatomical prostate enucleation using different laser technologies is a well-established surgical approach for the treatment of BPH.
The purpose of this prospective randomized study is to compare the efficiency and safety of three commonly used laser systems-Holmium:YAG, Thulium:YAG, and Thulium Fiber Laser (TFL)-during anatomical prostate enucleation.
The primary objective of the study is to evaluate laser efficiency by measuring grams of enucleated prostate tissue per joule (g/J) using intraoperative laser device data. Secondary outcomes include changes in International Prostate Symptom Score (IPSS) and the occurrence of postoperative urinary incontinence.
All laser systems used in this study are part of routine clinical practice, and no additional diagnostic procedures or treatments will be performed for study purposes
Patients diagnosed with benign prostatic hyperplasia (BPH) and scheduled for anatomical prostate enucleation
Presence of a prostate and clinical indication for surgical treatment
Age between 50 and 80 years
History or suspicion of prostate cancer
Previous prostate surgery
Presence of neurogenic bladder or significant lower urinary tract dysfunction unrelated to BPH
Active urinary tract infection at the time of surgery