Comparison of Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity Medical Center Ho Chi Minh City (UMC)

About this trial

Evidence of implementation of laparoscopic total gastrectomy (LTG) for locally advanced gastric cancer (GC) remains inadequate. This study aimed to compare short- and mid-term outcomes of LTG versus open total gastrectomy (OTG) for cT2-4a GC.

Eligibility criteria

Qualifiers

Pathologic finding by gastric endoscopy: confirmed gastric adenocarcinoma

Age: 18 - 80 year old

Tumor required total gastrectomy for radical treatment

Preoperative cancer stage (CT scan stage): cT2-4aNanyM0

Disqualifiers

Concurrent cancer or patient who was treated due to other cancer before the patient was diagnosed gastric cancer

Bulky lymph node andd/or Para-aortic lymph node metastasis

Combined esophagectomy due to invading to the esophagus

Pregnant patient

Trial design

Treatments tested in this trial

  • Laparoscopic gastrectomy

Treatment groups

210 Participants
are divided into 2 treatment groups