Comparison of Milrinone and Epinephrine on TAPSE

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorMansoura University

About this trial

Cardiopulmonary bypass (CPB) is a critical technology in cardiac surgery, allowing for the temporary replacement of the heart and lung functions during intricate surgical procedures. it has significant post-surgical complications, the most important complications of CPB is right ventricle (RV) dysfunction. Diagnosis and management of RV dysfunction is crucial for maintenance of hemodynamic stability and organ function in early post-operation period and prognostic for later phase.

Eligibility criteria

Qualifiers

American Society of Anesthesiologists (ASA) physical status II & III

Age between 18 and 70 years

Both Gender

Body mass index less than 40 kg/m2

Disqualifiers

Patient refusal.

Preoperative RV impairment

Pulmonary hypertension (estimated pulmonary artery systolic pressure > 50 mmHg)

Patients with any contraindications to Transesophageal echocardiography (TEE)

Trial design

Treatments tested in this trial

  • Epinephrine
  • Milrinone Injection

Treatment groups

102 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators