Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia
ConditionTrigeminal Neuralgia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorZagazig University
About this trial
The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults.
The main questions it aims to answer are:
* Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia? * What is the safety profile and complication rate of PRF versus PRF + TRF?
Researchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication.
Participants will:
* Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve. * Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.
Eligibility criteria
Qualifiers
Adults aged 18-60 years.
Diagnosis of classical trigeminal neuralgia, as per the International Classification of Headache Disorders criteria
Patients experiencing unilateral, episodic facial pain for at least six months with a Numeric Rating Scale (NRS) score greater than 6, despite medical treatment.
Able to provide informed consent.
Disqualifiers
Patients with secondary trigeminal neuralgia (e.g., due to tumors, multiple sclerosis).
Previous surgery or radiofrequency treatment for trigeminal neuralgia.
Pregnant or breastfeeding women.
Known allergies to anesthetics or other agents used in the procedure.
Trial design
Treatments tested in this trial
- Pulsed Radiofrequency (PRF)
- Pulsed and Thermal Radiofrequency (PRF + TRF)
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov