Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity Hospital Dubrava

About this trial

Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft. Subjects and methods: It is a single-blind prospective randomized study that would include at least 40 patients with an anterior cruciate ligament rupture. Patients would be randomly divided into two groups of minimally 20 patients each. Patients in the first study group would undergo ACL reconstruction with a muscle-tendon graft, while patients in the control group would be treated with the standard method of ACL reconstruction with a tendon graft.

Expected contribution to the field: The assumption is that the obtained results could enable a better understanding of the contribution of remaining muscle fibers on the tendon in anterior cruciate ligament reconstruction operations to the tendon to bone ingrowth and intra-articular remodeling of the graft of operated patients.

Eligibility criteria

Qualifiers

Clinically and radiologically confirmed anterior cruciate ligament (ACL) rupture.

Age between 18 and 50 years.

Intact posterior cruciate ligament and collateral ligaments.

Signed informed consent to participate in the study.

Disqualifiers

Previous ACL reconstruction of the same knee.

Inability to use a graft prepared by quadruple folding of the semitendinosus tendon.

Graft diameter < 7.5 mm.

MRI-confirmed unsuccessful meniscal healing after repair.

Trial design

Treatments tested in this trial

  • ACL reconstruction

Treatment groups

40 Participants
are divided into 4 treatment groups

Sponsors and collaborators