Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-17
SponsorCentre Hospitalier Universitaire de la Réunion

About this trial

This study aims to compare the accuracy of two different blood sampling methods from a central venous catheter (CVC) for measuring anti-Xa activity in children receiving unfractionated heparin (UFH) from this CVC. The results will be compared to a "gold standard" sample taken from an arterial catheter (KTA) whithout UFH. The objective is to identify a more reliable method for monitoring UFH, thereby reducing the risk of bleeding or thrombosis in these patients.

Eligibility criteria

Qualifiers

Minors aged 0 to 17 inclusive

Weight greater than or equal to 3.5 kg

Admitted to resuscitation or congenital cardiac intensive care

Requiring treatment with unfractionated heparin at curative doses administered via central venous access

Disqualifiers

Newborns < 37 weeks gestation

Patients treated by a humanitarian organization

Trial design

Treatments tested in this trial

  • blood sampling for measuring anti-Xa activity
  • measurement of anti-XA activity

Treatment groups

22 Participants
are divided into 1 treatment group

Locations

This trial has no locations