Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorJagiellonian University

About this trial

Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols. Replacing opioids with non-opioid analgesics, co-analgesics, and regional and local anesthesia techniques allows avoiding the adverse effects of opioids while maintaining satisfactory analgesia. This is of particular importance in bariatric surgery, where reducing the incidence of respiratory depression, sedation, opioid hyperalgesia, and postoperative nausea and vomiting is a priority. Standard non-opioid anesthesia (OFA) includes ketamine, lidocaine, and dexmedetomidine infusions, while regional techniques additionally reduce the need for analgesics. Despite the widespread use of these methods, there is no clear data on the superiority of any of them in bariatric procedures.

Eligibility criteria

Qualifiers

Patients over 18 years who underwent laparoscopic bariatric surgery

Must be able to sign agreement for study

Disqualifiers

Patients with a history of allergic reactions to drugs

Patients with a history of drug addiction

Patients with chronic pain who require analgesics

History of hospitalization for psychiatric disorders

Trial design

Treatments tested in this trial

  • Celiac Plexus Block
  • ESP block
  • Lidacaine

Treatment groups

300 Participants
are divided into 3 treatment groups

Sponsors and collaborators