Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorXinhua Hospital, Shanghai Jiao Tong University School of Medicine

About this trial

GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect(CSD) patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without GnRH-a, whether delayed period improving the CSD prognosis will be assessed.

Eligibility criteria

Qualifiers

Clearly diagnosed with CSD complicated with adenomyosis

Experiencing clinical features of abnormal uterine bleeding, prolonged menstrual flow (the duration of menstruation is more than 10 days).

The thickness of the remaining muscular layer of CSD was less than 3 mm.

Normal range of blood sugar and insulin

Disqualifiers

Indefinite diagnosis.

Malignant tumors.

With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).

Pregnant.

Trial design

Treatments tested in this trial

  • Leuprorelin

Treatment groups

94 Participants
are divided into 2 treatment groups