Comparison of Two Sedative Agents in Terms of Controlled Hypotension

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorHayatabad Medical Complex

About this trial

Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention. So, it provides a better visiblity of surgical filed to the surgeons.This RCT compares propofol infusion vs isoflurane inhalation for inducing controlled hypotension during endoscopic sinus surgery. The goal is to assess which agent better controls blood pressure, improves surgical field visibility, and impacts recovery. It likely measures outcomes like hemodynamics, bleeding, and surgeon satisfaction.

Eligibility criteria

Qualifiers

Either male/female Age 18-65 Patients undergoing endoscopic sinus surgery as per the operational definition

Disqualifiers

Patients with cardiovascular disease Patients with pregnancy Patients with coagulopathy Patients on beta blockers or calcium channel blockers

Trial design

Treatments tested in this trial

  • Propofol
  • Isoflurane

Treatment groups

136 Participants
are divided into 2 treatment groups

Sponsors and collaborators