Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorLaval University

About this trial

Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target. It is essential to have an accurate measurement of SpO2 in order to optimize the flow of oxygen or FiO2 administered to patients. The question arises as to the impact of these confounding factors on the FiO2 set during high-flow nasal oxygen therapy. The aim of the study is to evaluate the impact of the oxygenation target and the oximeter used on FiO2 in patients receiving high-flow nasal oxygen therapy.

Eligibility criteria

Qualifiers

≥ 18 years of age

Admiitted in intensive care unit

Presence of an arterial catheter

Ongoing on high flow nasal oxygen therapy with SpO2 between 88 and 100% with a FiO2 between 40 and 80% with the usual oximeter .

Disqualifiers

No SpO2 signal with oximeter in use

False nails or nail polish

Methemoglobinemia >0.015 on last available arterial gas

Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...)

Trial design

Treatments tested in this trial

  • Manual FiO2 titration with Philips oximeter (SpO2 target 90%)
  • Manual FiO2 titration with Nonin oximeter (SpO2 target 90%)
  • Manual FiO2 titration with Philips oximeter (SpO2 target 94%)
  • Manual FiO2 titration with Nonin oximeter (SpO2 target 94%)

Treatment groups

30 Participants
are divided into 4 treatment groups

Sponsors and collaborators