During thoracic surgery, one-lung ventilation (OLV) is associated with hypoxemia, lung injury, and perioperative respiratory complications. The level of positive-end expiratory pressure (PEEP) to apply during OLV remains controversial. The open-lung approach consists in setting a level of PEEP corresponding to the best lung compliance, using an esophageal catheter to measure the transpulmonary pressure. This approach has been effective in laparoscopic surgeries or acute respiratory distress syndrome, but has never been evaluated in thoracic surgery.
To be over 18 years old,
To be able to attend all scheduled visits and to comply with all trial procedures,
To be scheduled for a lung cancer resection surgery (performed by either video-assisted thoracoscopy or thoracotomy).
Non-carcinologic indication of lung resection (e.g. Lung volume reduction for bullous emphysema reduction, lung abscess),
Bilateral pulmonary resection surgery or history of lung resection surgery,
Lung resection under sternotomy
Non intubated video-assisted thoracoscopy