About this trial
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
Eligibility criteria
Qualifiers
First ever ischemic stroke
Subacute phase of stroke 3-6 months post onset
Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50
Disqualifiers
Previous injury or surgical intervention of vagus nerve
Patients with cardiac arrest and arrythmias
Uncontrolled hypertension
Apraxia
Trial design
Treatments tested in this trial
- Transcutaneous vagus nerve stimulation through auricular branch along with task specific exercises
- Transcutaneous vagus nerve stimulation through cervical branch along with task specific exercises