Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer

ConditionColon Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Turin, Italy

About this trial

An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.

Eligibility criteria

Qualifiers

American Society of Anesthesiologists(ASA) grade I-III.

Right colon cancer (*The right-sided location of the cancer is defined as the location from the caecum up to the proximal third of the transverse colon), preoperative assessment of tumor stage T2-T4a, any N or T any N+ according to the National Comprehensive Cancer Network(NCCN) clinical practice guidelines in oncology: colon cancer version 2.2015); no distant metastasis.

Informed consent

Disqualifiers

Age > 85 years old.

T1, N0

T4b, any N

BMI > 30.

Trial design

Treatments tested in this trial

  • Conventional Right hemicolectomy (Non-CME)
  • Right hemicolectomy with CME+CVL

Treatment groups

416 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Turin, Italy

Lead sponsor

Federico II University

Collaborator

Agnelli Hospital, Italy

Collaborator

Ospedale della Misericordia

Collaborator

Candiolo Cancer Institute - IRCCS

Collaborator

Maggiore Bellaria Hospital, Bologna

Collaborator

Università degli Studi di Ferrara

Collaborator

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Collaborator

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

Collaborator

Ospedale Policlinico San Martino

Collaborator

University of Rome Tor Vergata

Collaborator

S. Andrea Hospital

Collaborator

European Institute of Oncology

Collaborator