Compliance and Tolerance to Oral AntiBiotherapy in Osteoarticular Infections (OTABIO)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHospices Civils de Lyon
About this trial
Bone and joint infections (BJI) are most often bacterial infections that can occur after surgery or de novo. They are rarely fatal in the short term, but are associated with significant morbidity, impaired quality of life and significant costs. Treatment of BJI is based on antibiotic therapy, often combined with surgery. Antibiotic therapy, at high doses, lasts a minimum of 6 weeks. It can be responsible for severe adverse effects. These characteristics (prolonged duration, multiple daily doses, and adverse effects) are known to negatively affect treatment adherence in general.
Eligibility criteria
Qualifiers
≥ 18 years
Diagnosis of osteoarticular infection
Treatment with at least one oral antibiotic for a minimum expected duration ≥ 6 weeks with an expected end of treatment date
Patient who was informed and did not object to participate in the study
Disqualifiers
Treatment for BJI with oral antibiotic without end of treatment date
treatment for BJI with parenteral antibiotic only
patient who doesn't have a telephone number or who doesn't want to give it
Adults subject to a legal protection measure
Trial design
Treatments tested in this trial
- Tolerance and adherence to oral antibiotics in patients managed for BJI
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov