Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSwissmed Hospital
About this trial
People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.
Eligibility criteria
Qualifiers
Age 18 years or older
Elective repair of a large ventral abdominal wall hernia (including incisional hernia)
Preoperative botulinum toxin A preparation performed as part of the local prehabilitation pathway
Preoperative abdominal CT available
Disqualifiers
Severe preoperative respiratory failure judged to preclude standardized intraoperative respiratory mechanics assessment
Inability to obtain reliable static respiratory system compliance measurements at predefined timepoints
Hemodynamic instability preventing protocolized measurements (as judged by the anesthesiologist)
Trial design
Treatments tested in this trial
- Compliance-Guided Abdominal Wall Closure Decision Strategy
Treatment groups
50 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Swissmed Hospital
Lead sponsor
Medical University of Gdansk
Collaborator
Source ClinicalTrials.gov