About this trial
The objective of this research is to analyze the overall incidence of complications associated with a therapeutic maneuver known as alveolar opening and subsequent titration of positive end-expiratory pressure (PEEP) in pediatric patients with acute respiratory distress syndrome (ARDS). These procedures are part of the standard care provided in the Pediatric Intensive Care Unit (PICU) and are used to improve pulmonary oxygenation and respiratory mechanics. Through this study, we aim to gather information that will help improve the safety and effectiveness of these interventions in critically ill patients.
Eligibility criteria
Qualifiers
Patients under 14 years of age admitted to the HCANK PICU
More than 4 hours of invasive mechanical ventilation (IMV)
An oxygenation index (OI) ≥4 or an oxygen saturation index (OSI) ≥5
Indication for ARM and PEEP as determined by the treating team
Disqualifiers
Predicted body weight (PBW) >45.5 kg
Recent pulmonary resection surgery (<7 days)
Presence of broncho-pleural fistula or peri-tube leak >25% of the tidal volume
Hemoglobin decline <7 g/dL
Trial design
Treatments tested in this trial
- Alveolar Opening Maneuver and PEEP Titration (AOM+P)