Complications of the Alveolar Opening Maneuver in Children on Mechanical Ventilation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-14
SponsorHospital de Alta Complejidad en Red

About this trial

The objective of this research is to analyze the overall incidence of complications associated with a therapeutic maneuver known as alveolar opening and subsequent titration of positive end-expiratory pressure (PEEP) in pediatric patients with acute respiratory distress syndrome (ARDS). These procedures are part of the standard care provided in the Pediatric Intensive Care Unit (PICU) and are used to improve pulmonary oxygenation and respiratory mechanics. Through this study, we aim to gather information that will help improve the safety and effectiveness of these interventions in critically ill patients.

Eligibility criteria

Qualifiers

Patients under 14 years of age admitted to the HCANK PICU

More than 4 hours of invasive mechanical ventilation (IMV)

An oxygenation index (OI) ≥4 or an oxygen saturation index (OSI) ≥5

Indication for ARM and PEEP as determined by the treating team

Disqualifiers

Predicted body weight (PBW) >45.5 kg

Recent pulmonary resection surgery (<7 days)

Presence of broncho-pleural fistula or peri-tube leak >25% of the tidal volume

Hemoglobin decline <7 g/dL

Trial design

Treatments tested in this trial

  • Alveolar Opening Maneuver and PEEP Titration (AOM+P)

Treatment groups

143 Participants
are divided into 1 treatment group