Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity Hospital Ostrava
About this trial
The aim of this project is to perform a detailed evaluation of upper esophageal sphincter function and the swallowing mechanism in patients with swallowing disorders or suspected extraesophageal reflux using high-resolution manometry with impedance and 24-hour pH-impedance monitoring.
Eligibility criteria
Qualifiers
age 18-75 years
patients with swallowing difficulties suspected of having a functional oesophageal disorder or patients with clinical signs of extra-oesophageal reflux (Reflux Symptom Index [RSI] ≥ 13 or Reflux Symptom Score-12 [RSS-12] ≥ 11) signed informed consent
Disqualifiers
patients with a diagnosed tumor of the esophagus or upper airway, or with strong clinical suspicion of a tumor of the esophagus or upper airway
severe neurological disease affecting swallowing
pregnancy
surgery involving the head, neck, or esophagus within the last 6 months
Trial design
Treatments tested in this trial
- High resolution oesophageal manometry with impedance
- 24-hour pH metry
Treatment groups
160 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov