Comprehensive Respiratory Training Exercise Program in Obstructive Sleep Apnea

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-65
SponsorNational Cheng-Kung University Hospital

About this trial

Obstructive sleep apnea (OSA) is a multi-factorial sleep disorder. Complete collapse or partial collapse in the airway increases the risk of developing cardiovascular and kidney-related disease in OSA patients. Resulting in an increase in medical expenses and workload for the healthcare worker. Multilevel of upper airway muscles especially the genioglossus muscle showed to contribute to airway obstruction as it fatigues easily. The endurance level of OSA patients was shown to be significantly lower. Therefore, the goal of this experimental study is to assess the feasibility and effectiveness of a comprehensive respiratory training exercise program on cardiorespiratory endurance, airway muscle function, and sleep parameters in patients with obstructive sleep apnea (OSA). Aside from exploring the therapeutic effect, the results of the study will be used to explore the mechanism of the treatment in relation to the changes in the OSA severity.

Eligibility criteria

Qualifiers

Newly diagnosed with OSA (AHI≥ 5 events per hour)

Age between 20 to 65 years old

BMI of 18-30 kg.m-2

Disqualifiers

Central or mixed types of sleep apnea

Neuromuscular disease

Severe cardiovascular disease

Active psychiatric disease

Trial design

Treatments tested in this trial

  • Comprehensive Respiratory Training Exercise Program
  • Sleep hygiene education

Treatment groups

150 Participants
are divided into 2 treatment groups