Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorMayo Clinic
About this trial
The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.
Eligibility criteria
Qualifiers
Palpable penile plaque
Dorsal, lateral, or dorsolateral penile curvature
Penile curvature > 30 degrees and < 90 degrees as measured using goniometer during objective curvature assessment
Non-calcified plaque or grade 1 calcification ("stippling", no shadowing) as determined by penile duplex Doppler ultrasound (PDDU)
Disqualifiers
Prior intralesional injections or surgery for PD.
Severe baseline penile pain.
Moderate or severe baseline ED based on IIEF-EF domain.
History of low intensity shockwave therapy for sexual dysfunction (ED or PD).
Trial design
Treatments tested in this trial
- Collagenase Clostridium Histolyticum
- Storz Duolith LiSWT
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov