Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer

ConditionRectum Cancer
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorChanghai Hospital

About this trial

In this clinical trial, the investigators compared anal function, genitourinary function, quality of life, perioperative safety, and oncological prognosis after CSPO for patients with low rectal cancer, using ISR as a control, to provide high-level evidence-based medical evidence for the choice of anorectal preservation surgical approaches for patients with low rectal cancer.

Eligibility criteria

Qualifiers

Age: 18-75 years;

Pathologically confirmed: moderately & well-differentiated rectal cancer;

Low rectal cancer: lower edge of tumor ≦5cm from anal verge or ≦2cm from dentate line;

Tumor diameter: ≤3cm or <1/3 bowel circumference;

Disqualifiers

Combination of synchronous or metachronous (within 5 years) malignant tumors;

Combined distant metastasis of the tumor;

Combined intestinal obstruction, intestinal perforation, or intestinal bleeding requiring emergency surgery;

Combined psychiatric disorders that do not allow them to understand and participate in the study;

Trial design

Treatments tested in this trial

  • CSPO
  • ISR

Treatment groups

84 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators