Confounding Factors of Chronic Endometritis in Women With Reproductive Failure
ConditionIVF
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age20-45
SponsorChinese University of Hong Kong
About this trial
The aim of the study is to investigate the confounding factors of chronic endometritis and therapeutic benefits of antibodies targeting plasma cells in women with reproductive failure.
Eligibility criteria
Qualifiers
Age 20-45 years;
Women with a history of 2 or more consecutive miscarriages before 24 weeks of gestation12; or
Women who failed to conceive after unprotected intercourse for one year; or
Women who failed failure to achieve a clinical pregnancy after two consecutive cycles of IVF, ICSI or frozen embryo replacement cycles where the cumulative number of transferred embryos is no less than four for day-2 embryos and no less than 2 for day-5 embryos (blastocysts), with all embryos being of good quality.
Disqualifiers
Uncorrected uterine anomalies, such as the septate or bicornuate uterus, fibroids (submucous/intramural);
Untreated hydrosalpinx;
History of antiphospholipid syndrome;
Known clinical autoimmune disease;
Trial design
Treatments tested in this trial
Treatment groups
720 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov