Conservative Treatment in Patients With Supraspinatus Tendon Injury.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-75
SponsorMedical University of Lodz

About this trial

Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is recommended. In cases of minor injuries, physiotherapy is as effective as surgical intervention.

The aim of this study is: (1) to compare the speed, effectiveness, and durability of four implemented interventions in improving sleep quality, pain, and shoulder function, (2) to select the most optimal form of conservative treatment for patients with shoulder pain affecting sleep quality, and (3) to evaluate the expression of brain-derived neurotrophic factor (BDNF) and proBDNF (precursor) at the mRNA protein level before the planned intervention (T0), 1 month (T1), 3 months (T3), and 6 months (T6) after intervention.

The study results can assist physicians and physiotherapists in providing patients with therapy that not only relieves pain and improves function but also augments sleep quality, an aspect often overlooked in the literature yet greatly impacting patients\' quality of life.

Eligibility criteria

Qualifiers

Symptomatic partial incomplete thickness tear of the supraspinatus tendon, with a length below 1 cm and not exceeding 50% of the tendon thickness, confirmed by ultrasound examination.

Sleep disturbance symptoms for at least 1 month due to shoulder pain - PSQI score > 5.

Shoulder pain disrupting the quality of sleep.

BMI < 30.

Disqualifiers

Other accompanying pain symptoms.

History of shoulder surgery.

Coexistence of psychiatric or neurological disorders.

Presence of comorbidities that may disrupt sleep.

Trial design

Treatments tested in this trial

  • 1ml of Depo-Medrol® injection
  • Rehabilitation
  • Nerve block with 4ml of 2% lidocaine
  • Tropocells® PRP injection

Treatment groups

40 Participants
are divided into 4 treatment groups

Sponsors and collaborators