Constant Current Versus Constant Voltage Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorXuanwu Hospital, Beijing

About this trial

To compare the efficacy, programming burden, power consumption, and physicians' and patients' satisfaction between current mode and voltage mode of deep brain stimulation in each period one year after surgery.

Eligibility criteria

Qualifiers

Patients with idiopathic Parkinson's disease

Aged 18 to 75, no limited sex

After bilateral STN-DBS, yet not powered on

Disqualifiers

Mental disorders or dementia

Pregnant, lactating women or women who are unable to take effective measures to prevent pregnancy

Serious health conditions, such as tumors, liver or kidney diseases, etc.

Epilepsy or other seizure disorders

Trial design

Treatments tested in this trial

  • Constant current (CC) subthalamic nucleus deep brain stimulation
  • Constant voltage (CV) subthalamic nucleus deep brain stimulation

Treatment groups

180 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Xuanwu Hospital, Beijing

Lead sponsor

Beijing Pins Medical Co., Ltd

Collaborator

Chinese PLA General Hospital

Collaborator

Tianjin Huanhu Hospital

Collaborator

Kunming Sanbo Brain Hospital

Collaborator

Xijing Hospital

Collaborator

The First People's Hospital of Changde City

Collaborator

The General Hospital of Southern Theater Command

Collaborator

The First Affilated Hospital of the Medical College, Shihezi University

Collaborator

RenJi Hospital

Collaborator

Changshu Hospital of Traditional Chinese Medicine

Collaborator

Hainan General Hospital

Collaborator

Affiliated Hospital of North Sichuan Medical College

Collaborator

Second Affiliated Hospital of Bengbu Medical College

Collaborator