Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorGuy's and St Thomas' NHS Foundation Trust

About this trial

The aim of this study is to better understand the relationship between pleural effusions and breathlessness in patients with unilateral pleural effusions and breathlessness who require pleural fluid removal for its management.

Eligibility criteria

Qualifiers

Age 18 years or above

Has a unilateral pleural effusion AND

require thoracocentesis OR

chest drain insertion (main study only) OR

Disqualifiers

Inability to consent

Any contraindications to the proposed pleural procedure

Haemodynamic or clinical instability that precludes from the safe completion of required pre-procedural measurements

Inability to identify surface landmarks for surface EMG electrode placement

Trial design

Treatments tested in this trial

  • Surface parasternal eletromyogram
  • Surface diaphragm electromyogram
  • Parasternal muscle ultrasound
  • Breathlessness assessment

Treatment groups

124 Participants
are divided into 1 treatment group