Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorM.D. Anderson Cancer Center

About this trial

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.

Eligibility criteria

Qualifiers

The patient will receive stereotactic body radiotherapy in the Thoracic Radiation Oncolcogy Service at MD Anderson.

Disqualifiers

The patient has a contra-indication for using a CPAP device.

The patient has not signed a study-specific informed consent for this study.

The patient is uncooperative.

The patient has reduced consciousness.

Trial design

Treatments tested in this trial

  • Biphasic Positive Airway Pressure
  • Computed Tomography
  • Continuous Positive Airway Pressure
  • Deep Inspiration Breath Hold
  • Radiation Therapy Treatment Planning and Simulation
  • Stereotactic Body Radiation Therapy

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators

M.D. Anderson Cancer Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator