Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block

ConditionPain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-75
SponsorUniversity Hospitals Cleveland Medical Center

About this trial

As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block. Through the needle, a small catheter will be placed in the participants back and the needle removed. Approximately one hour prior to the start of surgery, a numbing medication (ropivacaine, similar to Novocaine) in combination with dexmedetomidine (a pain medicine that is used in nerve block and that is not a narcotic) and contrast dye (iohexol) will be injected through the catheter. Participants will then go through the QST procedure (test of buzzing sensation and temperature sensation through pads applied to their skin) to assess the numb areas and then head to the operating room. In the operating room, the catheter will be removed after the surgeon obtains baseline CT scan images of the spine. Once surgery is completed, investigators will record pain scores over the next four days in the hospital and the amount of pain medication needed for controlling pain related to the surgery.

Eligibility criteria

Qualifiers

Age range: Adult patients 21-75 years of age

ASA status: I-III

Planned lumbar spine fusion involving no more than three levels

Ability to ambulate prior to surgery

Disqualifiers

Previous lumbar spine surgery

Metastatic cancer with involvement of the lumbar spine

eGFR < 60 mL/min/1.73m2

Active liver disease (hepatitis or cirrhosis)

Trial design

Treatments tested in this trial

  • Ropivacaine (Epidural analgesia)
  • Dexmedetomidine
  • Iohexol
  • QST Procedure

Treatment groups

32 Participants
are divided into 1 treatment group