Contribution of Multicenter Expertise and Deformable Fusion Software for Re-irradiations With Curative Intent
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Leon Berard
About this trial
We propose to evaluate the contribution of a standardized process combining,
* a validation of re-irradiation indications by a group of multi-professional experts (radiotherapists and physicists) and, * a collective validation of the accumulation of doses on all the organs of the anatomical region concerned obtained using deformable fusion software (MiM) allowing the accumulation of doses in terms of Equivalent Dose 2 Grays (EQD2).
The primary objective of this study is to determine the rate of patients for whom this process has changed the treatment plan.
Eligibility criteria
Qualifiers
Age ≥ 18 years when signing the consent form
Oligo-metastases or oligo-progression (< 5 metastases in less than 3 sites)
Second non-metastatic cancer
Isolated local recurrence
Disqualifiers
Indication of intracranial, prostate, rectum or esophagus re-irradiation
Diagnosis of multi-metastatic cancer
PS ECOG ≥ 2
Impossibility to interrupt current treatment with a tyrosine kinase inhibitor or other systemic treatment (excluding hormonal therapy) which may potentiate the rays effects (duration of wash-out according to treatment instructions)
Trial design
Treatments tested in this trial
- Multidisciplinary and multicenter validation of re-irradiation with curative intent
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov