Conventional Ultrafiltration Versus Dilutional Ultrafiltration in Pediatric CPB Patients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-5
SponsorAkron Children's Hospital
About this trial
The investigators will be comparing two different filtration methods on cardiopulmonary bypass for pediatric heart surgery patients. Three blood tests will be taken from the patient to compare which filtration method is better at decreasing post-cardiopulmonary bypass inflammation caused by the heart-lung machine.
Eligibility criteria
Qualifiers
Males and females less than 5 years of age
Cardiac operations utilizing CPB
Cardiac reoperations utilizing CPB
Disqualifiers
Patients greater than 5 years of age.
Any active SYSTEMIC noncardiac disease expected to raise patient baseline CRP levels to above normal levels (>1mg/dL). Since CRP levels correlate with the severity of most skin disease, patients with active dermatitis issues on the day of surgery will be excluded from the study. Patients with autoimmune diseases including RA, SLE, IBD (Crohn's disease, ulcerative colitis), Kawasaki disease and patients experiencing active infections will be excluded from the study.
Any noncardiac disease not well controlled (ex. Asthma not properly controlled with medication, etc.)
Recent viral illness (ex. Positive COVID/flu test 30 days prior to surgery)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
100 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov