This randomized study compares the effects of conventional (right ventricular pacing in patients with LVEF ≥ 40% and cardiac resynchronization therapy in patients with LVEF \< 40 %) versus left bundle branch pacing on left ventricular remodelling in patients with reduced left ventricular ejection fraction (\< 50 %) that need permanent pacemaker implantation after transcatheter aortic valve implantation (TAVI).
Indication for permanent pacemaker implantation after transcatheter aortic valve implantation (during the same hospitalization)
Left ventricular ejection fraction < 50 %.
Unsuccessful TAVI procedure with life expectancy < 1 year
Ischemic cardiomyopathy with interventricular septal fibrosis (at least echocardiographic signs of fibrosis)
Severe kidney failure (glomerular filtration rate < 30 ml/min)
Previous permanent pacemaker